Physical Models of Living Matters - The 3rd Symposium of Physical Biology and Biological Physics

Session

Session II

Aug 30, 2024, 3:40 PM

205 Meeting Room (The Aspire Resort, Taoyuan)

Conveners

Session II

• Grace Pen-hsiu Chao

19. Probing the Nanoscale Membrane Topography in Cells

Prof. Wenting Zhao (Nanyang Technological Unviersity)

8/30/24, 3:40 PM

Cell membranes serve as a central platform to host a variety of proteins essential for cellular activities such as cell signaling, morphogenesis, and membrane trafficking. At the same time, the membranes also undergo drastic morphological changes in a number of essential processes, such as endocytosis, intracellular trafficking, and cytokinesis, etc. An intriguing yet challenging question to...

8. Dynamics of force-regulated branched actin network density

Prof. Tai-de Li (CUNY)

8/30/24, 4:10 PM

The assembly of branched actin networks provides the driving force for numerous cell motilities of all eukaryotic cells. While pushing the cytoplasm membrane moving forward, the networks are also polymerizing under a counter force. At the leading edge of the cell motilities, such as Lamellipodium, the pushing force and network formation are dynamically regulated by nucleation, elongation, and...

37. To repair or regenerate, it is a matter of matrix stiffness

Prof. Ming Jer Tang (National Cheng Kung University College of Medicine)

8/30/24, 4:30 PM

We have worked on the influence of matrix stiffness on cellular physiology in epithelial cells and fibroblasts as well, which plays a very important role in pathophysiology of organ and tissue fibrosis. The current research theme of my research has been to unveil the mechanobiological mechanism of converting wound repair into regeneration. We have discovered that breaking symmetry of cell...

33. Characterization of Megadalton MALDI Ions with Linear Ion Trap Mass Spectrometer

Prof. Wen Ping Peng (NDHU)

8/30/24, 4:50 PM

Detecting megadalton matrix-assisted laser desorption/ionization (MALDI) ions with linear ion trap mass spectrometer (LIT-MS) is a technical challenge. In this talk, we employ MALDI LIT- MS to successfully analyze megadalton protein, polymer, and proteasome ions. A homebuilt linear ion trap mass spectrometer (LIT-MS) equipped with a charge sensing particle detector (CSPD) is used for high mass...

34. Self-organized cellular patterns direct waves of cell death

Prof. Sheng-hong Chen (Academia Sinica)

8/30/24, 5:10 PM

Large-scale cell death is widely observed during embryonic development and various human pathological conditions. However, a systems-level understanding for how large-scale cell death emerges had been lacking. Harnessing time-lapse imaging, chemical/genetic perturbations and mathematical modeling, we show how metabolic stress quantitatively modulate cellular state for the emergence of redox...