The 4th Physical Biology and Biological Physics Symposium - The Biological Physics Across Scales From Single Molecules to Organisms

Session

Multiplexed Nanoscopy Uncovers the Molecular Architecture of Mammalian Centrioles

Session V - 1 Chair: Yu-chun Yolanda Lin

17 Jan 2026, 09:00

Conveners

Multiplexed Nanoscopy Uncovers the Molecular Architecture of Mammalian Centrioles

• Tony Yang (National Taiwan University)

42. Multiplexed Nanoscopy Uncovers the Molecular Architecture of Mammalian Centrioles

Prof. Tony Yang (National Taiwan University)

Invited Speaker

Direct stochastic optical reconstruction microscopy (dSTORM) overcomes the diffraction limit of light, enabling nanoscale visualization (~10–20 nm) of subcellular structures. Yet, achieving true ultrastructural resolution with dSTORM alone remains challenging. Recent advances combining dSTORM with expansion microscopy (ExM)—which physically enlarges specimens via a swellable polymer...