Workshop on Random Walks in Biological Physics with Focus on DNA and chromosome structure

Lecture 4: DNA Topology and Its Regulation In Vivo (John F. Marko)

Not scheduled

1h 15m

1F Auditorium (Institute of Physics, Academia Sinica)

Lecture 4

Speaker

Prof. John F. Marko (Northwestern University)

Description

DNA Topology and its Regulation in vivo. Polymer entanglement; entanglement and knotting lengths; chromosome dynamics during cell cycle; lengthwise compaction model; active loop extrusion model; SMC complexes (condensin, cohesin, SMC5/6 bacterial SMCs); experiments supporting
loop extrusion model.